Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19757723 | 0.76 | BACE1 (0.34) | ALDH1A1NPC1RAB9AKDM4ELMNA | |
| SCHEMBL364027 | 0.74 | MAPK1 (0.52) | PTGDR2MAPK1ALDH1A1NPC1TSHR | |
| SCHEMBL29776868 | 0.74 | ALDH1A1 (0.42) | MAPK1ALDH1A1HPGDSMN1; SMN2ESR2 | |
| SCHEMBL16562891 | 0.74 | ALDH1A1 (0.42) | MAPK1ALDH1A1HPGDSMN1; SMN2ESR2 | |
| SCHEMBL19190198 | 0.74 | PTPRC (0.56) | PTGDR2MAPK1ALDH1A1NPC1TSHR | |
| SCHEMBL30006434 | 0.74 | MAPK1 (0.52) | PTGDR2MAPK1ALDH1A1NPC1TSHR | |
| SCHEMBL6326863 | 0.74 | ESR2 (0.48) | GABRA1GABRA5GABRA2GABRB2GABRA3 | |
| SCHEMBL3007914 | 0.73 | MAPK1 (0.58) | PTGDR2MAPK1ALDH1A1NPC1TSHR | |
| SCHEMBL14816711 | 0.72 | NPC1 (0.36) | MAPK1ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL16943347 | 0.71 | ALDH1A1 (0.48) | PTGDR2MAPK1ALDH1A1NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180006225-A1 | Compositions with Triarylamine Derivatives and Oled Device Containing the Same | DOW GLOBAL TECHNOLOGIES LLC | 2018-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180006225-A1 | Compositions with Triarylamine Derivatives and Oled Device Containing the Same | DRD2, NSD2, DRD4 | GABRA1 4378/4885GABRA5 3847/4885GABRA2 4079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.