Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.32 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852486 | 0.77 | RAB9A (0.42) | BACE1ESR2AKT1AKT2ENPP3 | |
| SCHEMBL15453485 | 0.77 | PTGS2 (0.37) | BACE1TDO2ESR2AKT1AKT2 | |
| SCHEMBL19757724 | 0.76 | GABRA1 (0.42) | ESR2MAPTNPC1RAB9AKDM4E | |
| SCHEMBL28310672 | 0.76 | ALDH1A1 (0.48) | BACE1TDO2SMARCA2SMARCA4PBRM1 | |
| SCHEMBL16562891 | 0.73 | ALDH1A1 (0.42) | BACE1ESR2TDP1AKT1AKT2 | |
| SCHEMBL29776868 | 0.73 | ALDH1A1 (0.42) | BACE1ESR2TDP1AKT1AKT2 | |
| SCHEMBL20180021 | 0.72 | SQOR (0.46) | BACE1TDO2ESR2AKT1AKT2 | |
| SCHEMBL13995119 | 0.71 | GPR84 (0.38) | BACE1TDO2ESR2TDP1ENPP1 | |
| SCHEMBL31367772 | 0.71 | L3MBTL1 (0.46) | TDP1PTGS2MAPTNPC1RAB9A | |
| SCHEMBL30679836 | 0.69 | PTGER4 (0.38) | TDP1PTGS2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180006225-A1 | Compositions with Triarylamine Derivatives and Oled Device Containing the Same | DOW GLOBAL TECHNOLOGIES LLC | 2018-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180006225-A1 | Compositions with Triarylamine Derivatives and Oled Device Containing the Same | DRD2, NSD2, DRD4 | BACE1 1322/4885TDO2 75/4885PIN1 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.