SCHEMBL19762835

SCHEMBL19762835

O=C(O)C1CCC(O)C(O)C1O

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 5/20 0.42
SLC1A2 P43004 3/20 0.37
SLC1A1 P43005 2/20 0.37
GABRR2 P28476 1/20 0.36
HPSE Q9Y251 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14191347 1.00 GABRR1 (0.42) GABRR1SLC1A2SLC1A1GABRR2HPSE
SCHEMBL22602662 1.00 GABRR1 (0.42) GABRR1SLC1A2SLC1A1GABRR2HPSE
Water SCHEMBL31468829 0.97 GABRR1 (0.40) GABRR1SLC1A2SLC1A1GABRR2HPSE
SCHEMBL25347129 0.92 GABRR1 (0.43) GABRR1SLC1A2SLC1A1GABRR2
SCHEMBL3227345 0.92 GABRR1 (0.43) GABRR1SLC1A2SLC1A1GABRR2
SCHEMBL16380722 0.81 GABRR1 (0.43) GABRR1SLC1A2SLC1A1GABRR2
SCHEMBL163825 0.81 GABRR1 (0.43) GABRR1SLC1A2SLC1A1GABRR2
SCHEMBL30756696 0.81 GABRR1 (0.43) GABRR1SLC1A2SLC1A1GABRR2
SCHEMBL18253254 0.81 GABRR1 (0.43) GABRR1SLC1A2SLC1A1GABRR2
SCHEMBL17484815 0.81 GABRR1 (0.43) GABRR1SLC1A2SLC1A1GABRR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4380633-A2 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF Rayzebio, Inc. (US) 2024-06-12 EP claimed
WO-2023191839-A9 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF RAYZEBIO, INC. (US) 2023-11-09 WO claimed
WO-2023191839-A2 STABILIZED COMPOSITIONS OF RADIONUCLIDES AND USES THEREOF RAYZEBIO, INC. (US) 2023-10-05 WO claimed
EP-4583979-A1 CYTOTOXIC IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPY MyricX Pharma Limited (GB) 2025-07-16 EP disclosed
CN-119997982-A Antibody drug conjugates comprising NMT inhibitors and uses thereof 迈里克斯制药有限公司 2025-05-13 CN disclosed
CN-119968369-A Cytotoxic imidazo [1,2-a ] pyridine compounds and their use in therapy 迈里克斯制药有限公司 2025-05-09 CN disclosed
WO-2024052685-A1 CYTOTOXIC IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AND THEIR USE IN THERAPY MyricX Pharma Limited (GB) 2024-03-14 WO disclosed
EP-3658109-A1 COOLING AND FLAVOR BOOSTING COMPOSITIONS Firmenich SA (CH) 2020-06-03 EP disclosed
WO-2019070906-A1 PROBE FOR SELECTIVELY CHARACTERIZING ENZYMES INVOLVED IN XENOBIOTIC METABOLISM AND METHOD OF MAKING AND USING THE SAME WRIGHT AARON T (US) 2019-04-11 WO disclosed
US-20180002275-A1 HYPDH INHIBITORS AND METHODS OF USE FOR THE TREATMENT OF KIDNEY STONES WAKE FOREST UNIVERSITY HEALTH SCIENCES 2018-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180002275-A1 HYPDH INHIBITORS AND METHODS OF USE FOR THE TREATMENT OF KIDNEY STONES XDH, GLS, GRHPR GABRR1 1840/4885SLC1A2 1748/4885SLC1A1 1416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.