Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 10/20 | 0.53 |
| ▸ | NPC1 | O15118 | 10/20 | 0.53 |
| ▸ | GAA | P10253 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20625512 | 0.93 | KCNH2 (0.62) | KCNH2RAB9ANPC1GAAMAPT | |
| SCHEMBL21626743 | 0.83 | KCNH2 (0.73) | KCNH2RAB9ANPC1GAAMAPT | |
| SCHEMBL21626682 | 0.83 | KCNH2 (0.50) | KCNH2RAB9ANPC1GAAMAPT | |
| SCHEMBL19764155 | 0.81 | MPO (0.52) | KCNH2RAB9ANPC1GAAMAPT | |
| SCHEMBL19764152 | 0.80 | RAB9A (0.47) | KCNH2RAB9ANPC1GAAMAPT | |
| SCHEMBL1164776 | 0.78 | RAB9A (0.72) | KCNH2RAB9ANPC1GAAMAPT | |
| SCHEMBL1164775 | 0.78 | RAB9A (0.72) | KCNH2RAB9ANPC1GAAMAPT | |
| SCHEMBL29663046 | 0.78 | RAB9A (0.77) | KCNH2RAB9ANPC1GAAMAPT | |
| SCHEMBL22873999 | 0.78 | RAB9A (0.77) | KCNH2RAB9ANPC1GAAMAPT | |
| SCHEMBL20625511 | 0.76 | KCNH2 (0.58) | KCNH2RAB9ANPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180009741-A1 | BISHYDRAZONE-BASED ANTIFUNGAL AGENTS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180009741-A1 | BISHYDRAZONE-BASED ANTIFUNGAL AGENTS | DPM1, ERG28, SUCLG1 | KCNH2 2425/4885RAB9A 3483/4885NPC1 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.