Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28002427 | 0.94 | LMNA (0.36) | CYP1A2CYP2D6CYP2C19SIRT2MAPT | |
| SCHEMBL5537755 | 0.94 | LMNA (0.36) | CYP1A2CYP2D6CYP2C19SIRT2MAPT | |
| SCHEMBL13475130 | 0.94 | LMNA (0.36) | CYP1A2CYP2D6CYP2C19SIRT2MAPT | |
| SCHEMBL27771108 | 0.87 | NPC1 (0.37) | CYP1A2CYP2D6CYP2C19MAPTPGR | |
| SCHEMBL20233412 | 0.85 | LMNA (0.34) | CYP1A2CYP2D6CYP2C19MAPTPGR | |
| SCHEMBL17878900 | 0.80 | SIRT2 (0.34) | CYP1A2CYP2D6CYP2C19SIRT2NPC1 | |
| SCHEMBL16442400 | 0.78 | GPR3 (0.34) | SIRT2MAPTNPC1GAANFKB1 | |
| SCHEMBL2813518 | 0.77 | GPR3 (0.33) | SIRT2PGRNPC1GAANFKB1 | |
| SCHEMBL1452779 | 0.76 | PGR (0.38) | MAPTPGRMAPK1NPC1RAB9A | |
| SCHEMBL17067722 | 0.76 | CNR1 (0.38) | MAPK1NPC1NFKB1RAB9ANFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10032984-B2 | Polymer and organic light emitting device | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2018-07-24 | — | — | US | disclosed |
| US-20180019400-A1 | POLYMER AND ORGANIC LIGHT EMITTING DEVICE | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2018-01-18 | — | — | US | disclosed |