Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.34 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5537755 | 0.85 | LMNA (0.36) | SIRT2NPC1GAANFKB1RAB9A | |
| SCHEMBL28002427 | 0.85 | LMNA (0.36) | SIRT2NPC1GAANFKB1RAB9A | |
| SCHEMBL13475130 | 0.85 | LMNA (0.36) | SIRT2NPC1GAANFKB1RAB9A | |
| SCHEMBL16442400 | 0.84 | GPR3 (0.34) | SIRT2NPC1GAANFKB1RAB9A | |
| SCHEMBL19767752 | 0.80 | CYP1A2 (0.35) | SIRT2NPC1GAANFKB1RAB9A | |
| SCHEMBL27771108 | 0.79 | NPC1 (0.37) | TDP2NPC1GAANFKB1RAB9A | |
| SCHEMBL20233412 | 0.78 | LMNA (0.34) | NPC1GAANFKB1RAB9ANFKB2 | |
| SCHEMBL2813518 | 0.73 | GPR3 (0.33) | SIRT2NPC1GAANFKB1RAB9A | |
| SCHEMBL17882478 | 0.71 | PGR (0.43) | TDP2ESR1ESR2 | |
| SCHEMBL17067722 | 0.71 | CNR1 (0.38) | CNR1CNR2NPC1NFKB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160190458-A1 | POLYMER AND ORGANIC ELECTRONIC DEVICE | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160190458-A1 | POLYMER AND ORGANIC ELECTRONIC DEVICE | REV1, RER1, RIF1 | SIRT2 2091/4885NPY1R 145/4885NPY2R 668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.