Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 6/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19770367 | 0.89 | PIK3R1 (0.33) | DHFRFGFR1PIK3CA | |
| SCHEMBL20799377 | 0.81 | DHFR (0.41) | DHFR | |
| SCHEMBL19770368 | 0.78 | TSHR (0.34) | DHFRPIK3CA | |
| SCHEMBL17963621 | 0.77 | MAPT (0.36) | DHFRFGFR1 | |
| SCHEMBL21125475 | 0.76 | TSHR (0.34) | — | |
| SCHEMBL19770359 | 0.74 | KDM4E (0.35) | PIK3CA | |
| SCHEMBL17963639 | 0.72 | TSHR (0.34) | DHFRPIK3CA | |
| SCHEMBL17963641 | 0.72 | MAPT (0.42) | DHFR | |
| SCHEMBL20712621 | 0.67 | ADORA1 (0.36) | DHFRPIK3CA | |
| SCHEMBL28866573 | 0.67 | ALPL (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180015052-A1 | DESIGN, SYNTHESIS AND METHODS OF USE OF ACYCLIC FLEXMIER NUCLEOSIDE ANALOGUES HAVING ANTI-CORONAVIRUS ACTIVITY | UNIV MARYLAND (US) | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015052-A1 | DESIGN, SYNTHESIS AND METHODS OF USE OF ACYCLIC FLEXMIER NUCLEOSIDE ANALOGUES HAVING ANTI-CORONAVIRUS ACTIVITY | RNGTT, ACE, ADAR | DHFR 85/4885FGFR1 2760/4885PKM 1462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.