Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.31 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19779081 | 0.89 | NPSR1 (0.32) | NPSR1 | |
| SCHEMBL19779096 | 0.81 | NPSR1 (0.32) | NPSR1EGLN2TMPRSS2 | |
| SCHEMBL16710444 | 0.79 | NPSR1 (0.32) | NPSR1EGLN2TMPRSS2 | |
| SCHEMBL26288320 | 0.79 | EGLN2 (0.33) | NPSR1EGLN2OPRM1OPRD1OGFRL1 | |
| SCHEMBL16710859 | 0.79 | NPSR1 (0.32) | NPSR1EGLN2TMPRSS2 | |
| SCHEMBL16710860 | 0.78 | TMPRSS2 (0.38) | NPSR1EGLN2OPRM1OPRD1OGFRL1 | |
| SCHEMBL19779084 | 0.77 | POLRMT (0.39) | — | |
| SCHEMBL19779218 | 0.77 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL16708538 | 0.77 | NPSR1 (0.31) | NPSR1EGLN2TMPRSS2 | |
| SCHEMBL16710445 | 0.77 | NPSR1 (0.31) | NPSR1EGLN2TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180016280-A1 | PYRROLO[1,2-f][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016280-A1 | PYRROLO[1,2-f][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | SYNJ1, SARS1, SYNJ2 | NPSR1 508/4885EGLN2 1181/4885OPRM1 4190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.