Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785433 | 0.82 | ALDH1A1 (0.38) | ALDH1A1KMT2AKDM4ETDP1 | |
| SCHEMBL14811911 | 0.77 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1KMT2AKDM4E | |
| SCHEMBL24117439 | 0.76 | KMT2A (0.31) | ALDH1A1KMT2A | |
| SCHEMBL28309161 | 0.73 | JAK3 (0.41) | L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL29224288 | 0.73 | CTSK (0.35) | KMT2ACTSK | |
| SCHEMBL2594739 | 0.72 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1KMT2ARECQL | |
| SCHEMBL16246770 | 0.71 | KLKB1 (0.57) | — | |
| SCHEMBL8693769 | 0.70 | HCAR2 (0.40) | L3MBTL1ALDH1A1KMT2AHTT | |
| SCHEMBL22446424 | 0.69 | ELANE (0.31) | KDM4E | |
| SCHEMBL8693610 | 0.68 | HCAR2 (0.43) | L3MBTL1ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011628-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHARMACEUTICALS, INC. (BB) | 2018-01-18 | — | — | WO | disclosed |