SCHEMBL19781060

SCHEMBL19781060

c1ccc2c(c1)Sc1ccc3c([nH]c4ccc5ccccc5c43)c1S2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.41
CDK4 P11802 13/20 0.41
CCND1 P24385 13/20 0.41
CCNB2 O95067 2/20 0.41
CCNE2 O96020 2/20 0.41
CDK1 P06493 2/20 0.41
CCNB1 P14635 2/20 0.41
CCNE1 P24864 2/20 0.41
CDK2 P24941 2/20 0.41
CCNB3 Q8WWL7 2/20 0.41
PRKCG P05129 1/20 0.41
PRKCB P05771 1/20 0.41
PRKCA P17252 1/20 0.41
GSK3B P49841 1/20 0.41
MAP3K9 P80192 1/20 0.41
MAP3K11 Q16584 1/20 0.41
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRA1 P14867 1/20 0.37
GABRB1 P18505 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19781206 0.82 KIF11 (0.50) KIF11RAB9AKDM4ESIRT2SIRT1
SCHEMBL12219437 0.79 KIF11 (0.57) KIF11CDK4CCND1CCNB2CCNE2
SCHEMBL30730994 0.78 KIF11 (0.66) KIF11CDK4CCND1CCNB2CCNE2
SCHEMBL30914258 0.78 KIF11 (0.66) KIF11CDK4CCND1CCNB2CCNE2
SCHEMBL6523866 0.78 KIF11 (0.66) KIF11CDK4CCND1CCNB2CCNE2
SCHEMBL19781007 0.77 KIF11 (0.37) KIF11RAB9AKDM4ENPC1MEN1
SCHEMBL19781058 0.75 CDK4 (0.45) KIF11CDK4CCND1CCNB2CCNE2
SCHEMBL30320191 0.74 CYP2A6 (0.46) RAB9AKDM4ENPC1MEN1GAA
SCHEMBL26612938 0.74 CYP2A6 (0.46) RAB9AKDM4ENPC1MEN1GAA
SCHEMBL17876528 0.74 KIF11 (0.51) KIF11GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018012763-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2018-01-18 WO disclosed