SCHEMBL30320191

SCHEMBL30320191

c1ccc2c(c1)Sc1ccc3ccccc3c1S2

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.46
ALDH1A1 P00352 2/20 0.46
HSD17B10 Q99714 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
TSHR P16473 2/20 0.46
HIF1A Q16665 3/20 0.44
CYP1B1 Q16678 1/20 0.44
MAPT P10636 3/20 0.44
MEN1 O00255 1/20 0.44
NPC1 O15118 1/20 0.44
GAA P10253 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 1/20 0.44
NOX1 Q9Y5S8 1/20 0.44
HPRT1 P00492 1/20 0.42
BCHE P06276 2/20 0.38
SLC6A3 Q01959 1/20 0.38
CYP1A2 P05177 4/20 0.38
CYP2D6 P10635 3/20 0.37
CYP2C19 P33261 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26612938 1.00 CYP2A6 (0.46) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL26612879 0.93 ALDH1A1 (0.52) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL1796145 0.93 ALDH1A1 (0.52) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL26612945 0.91 ALDH1A1 (0.50) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL8208687 0.90 HPRT1 (0.54) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL26612926 0.88 ALDH1A1 (0.46) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL29278598 0.83 HPRT1 (0.56) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL19781206 0.79 KIF11 (0.50) CYP2A6ALDH1A1HSD17B10TDP1TSHR
SCHEMBL29216533 0.77 ALOX5 (0.32) ALOX5
SCHEMBL24186616 0.76 MAPT (0.40) CYP2A6ALDH1A1HSD17B10TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399200-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS Mitsubishi Gas Chemical Company, Inc. (JP) 2024-07-17 EP disclosed
WO-2023038156-A1 (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-03-16 WO disclosed