Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.41 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.41 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.41 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14978161 | 0.86 | USP2 (0.50) | USP2MEN1POLBKMT2APTPN1 | |
| SCHEMBL10177584 | 0.86 | USP2 (0.50) | USP2MEN1POLBKMT2APTPN1 | |
| SCHEMBL21101101 | 0.86 | USP2 (0.50) | USP2MEN1POLBKMT2APTPN1 | |
| SCHEMBL22389307 | 0.85 | KMT2A (0.42) | USP2MEN1POLBKMT2ALGALS9 | |
| SCHEMBL17073898 | 0.82 | LGALS3 (0.46) | USP2MEN1POLBKMT2ALGALS9 | |
| SCHEMBL24496369 | 0.80 | NT5E (0.46) | USP2MEN1POLBKMT2ALGALS9 | |
| SCHEMBL6220071 | 0.80 | PTPN1 (0.53) | USP2MEN1POLBKMT2ALGALS9 | |
| SCHEMBL6220068 | 0.80 | PTPN1 (0.53) | USP2MEN1POLBKMT2ALGALS9 | |
| SCHEMBL19786838 | 0.79 | PTPN1 (0.47) | USP2MEN1POLBKMT2ALGALS9 | |
| SCHEMBL19781228 | 0.79 | LMNA (0.49) | USP2MEN1POLBKMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10781175-B2 | Solid supports and phosphoramidite building blocks for oligonucleotide conjugates | AM CHEMICALS LLC (US) | 2020-09-22 | — | — | US | disclosed |
| US-20180016232-A1 | SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES | AM CHEMICALS LLC (US) | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10781175-B2 | Solid supports and phosphoramidite building blocks for oligonucleotide conjugates | NCL, PAICS, RTCB | USP2 4525/4885MEN1 2389/4885POLB 14/4885 |
| US-20180016232-A1 | SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES | NCL, PAICS, RTCB | USP2 4525/4885MEN1 2389/4885POLB 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.