Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SSTR5 | P35346 | 6/20 | 0.40 |
| ▸ | SSTR3 | P32745 | 5/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 3/20 | 0.40 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.38 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.38 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.38 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781228 | 0.93 | LMNA (0.49) | KMT2ALMNAPOLBMEN1USP2 | |
| SCHEMBL19781108 | 0.85 | USP2 (0.43) | KMT2APOLBMEN1USP2CYP2C9 | |
| SCHEMBL19769332 | 0.85 | KMT2A (0.38) | KMT2ALMNAPOLBMEN1USP2 | |
| SCHEMBL19613777 | 0.83 | LMNA (0.44) | KMT2ALMNAPOLBMEN1USP2 | |
| SCHEMBL14978161 | 0.81 | USP2 (0.50) | KMT2APOLBMEN1USP2CYP2C9 | |
| SCHEMBL21101101 | 0.81 | USP2 (0.50) | KMT2APOLBMEN1USP2CYP2C9 | |
| SCHEMBL10177584 | 0.81 | USP2 (0.50) | KMT2APOLBMEN1USP2CYP2C9 | |
| SCHEMBL10906318 | 0.81 | MCHR1 (0.46) | KMT2ALMNAPOLBSSTR5SSTR3 | |
| SCHEMBL19786845 | 0.81 | LMNA (0.53) | KMT2ALMNAPOLBMEN1USP2 | |
| SCHEMBL13786400 | 0.79 | LMNA (0.52) | KMT2ALMNAPOLBMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159458-A1 | SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES | AM CHEMICALS LLC (US) | 2023-05-25 | — | — | US | disclosed |
| US-20200277260-A1 | SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES | AM CHEMICALS LLC (US) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159458-A1 | SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES | NCL, PAICS, RTCB | KMT2A 1607/4885LMNA 2437/4885POLB 14/4885 |
| US-20200277260-A1 | SOLID SUPPORTS AND PHOSPHORAMIDITE BUILDING BLOCKS FOR OLIGONUCLEOTIDE CONJUGATES | NCL, PAICS, RTCB | KMT2A 1607/4885LMNA 2437/4885POLB 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.