Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC1 | P19801 | 11/20 | 0.53 |
| ▸ | AOC3 | Q16853 | 10/20 | 0.53 |
| ▸ | CYP2E1 | P05181 | 4/20 | 0.47 |
| ▸ | CYP2C8 | P10632 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.47 |
| ▸ | CYP2B6 | P20813 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | KDM6B | O15054 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23408471 | 0.85 | AOC1 (0.45) | AOC1AOC3CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL16257955 | 0.83 | AOC1 (0.65) | AOC1AOC3CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL10954433 | 0.76 | CYP2E1 (0.51) | AOC1AOC3CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL8047522 | 0.75 | AOC1 (0.61) | AOC1AOC3CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL873728 | 0.72 | CYP2E1 (0.49) | AOC1AOC3CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL7438728 | 0.72 | ALDH1A1 (0.46) | CA12CA1CA2CA9 | |
| SCHEMBL8271491 | 0.72 | CYP2E1 (0.49) | AOC1AOC3CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL7468680 | 0.72 | CYP2E1 (0.49) | AOC1AOC3CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL1369814 | 0.71 | CYP2E1 (0.47) | AOC1AOC3CYP2E1CYP2C8CYP2D6 | |
| SCHEMBL13625787 | 0.71 | CYP2E1 (0.47) | AOC1AOC3CYP2E1CYP2C8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572364-B2 | Pteridinone compounds and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-02-07 | — | — | US | disclosed |
| WO-2018013615-A1 | C7, C12, AND C16 SUBSTITUTED NEUROACTIVE STEROIDS AND THEIR METHODS OF USE | SAGE THERAPEUTICS, INC. (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572364-B2 | Pteridinone compounds and uses thereof | DPYD, PKD1, TYMP | AOC1 2771/4885AOC3 4369/4885CYP2E1 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.