Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24624723 | 0.85 | SMN1; SMN2 (0.32) | MEN1KMT2AFAAHMAPK1SMN1; SMN2 | |
| SCHEMBL26419977 | 0.82 | MAPK1 (0.47) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL2120083 | 0.82 | KMT2A (0.52) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL21189946 | 0.82 | LMNA (0.40) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL26707065 | 0.81 | MEN1 (0.43) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL2119932 | 0.80 | MEN1 (0.55) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL8402245 | 0.79 | SMN1; SMN2 (0.41) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL26316301 | 0.79 | POLB (0.33) | KMT2AALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL25083109 | 0.78 | MEN1 (0.44) | MEN1KMT2AFAAHMAPK1ALDH1A1 | |
| SCHEMBL24212536 | 0.78 | MEN1 (0.44) | MEN1KMT2AFAAHMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220177486-A1 | TYK2 INHIBITORS AND USES THEREOF | ALUMIS INC. | 2022-06-09 | — | — | US | disclosed |
| US-11253601-B2 | Nucleic acid conjugates and uses thereof | TRANSLATE BIO MA, INC. (US) | 2022-02-22 | — | — | US | disclosed |
| WO-2020185755-A1 | TYK2 INHIBITORS AND USES THEREOF | FRONTHERA U.S. PHARMACEUTICALS LLC (US) | 2020-09-17 | — | — | WO | disclosed |
| US-20190224326-A1 | NUCLEIC ACID CONJUGATES AND USES THEREOF | TRANSLATE BIO MA, INC. (US) | 2019-07-25 | — | — | US | disclosed |
| WO-2018013525-A1 | NUCLEIC ACID CONJUGATES AND USES THEREOF | TRANSLATE BIO MA, INC. (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11253601-B2 | Nucleic acid conjugates and uses thereof | FOLR1, SLC19A1, FOLR2 | MEN1 1700/4885KMT2A 2105/4885FAAH 4087/4885 |
| US-20220177486-A1 | TYK2 INHIBITORS AND USES THEREOF | TYK2, JAK1, JAK2 | MEN1 1061/4885KMT2A 42/4885FAAH 3640/4885 |
| US-20190224326-A1 | NUCLEIC ACID CONJUGATES AND USES THEREOF | FOLR1, SLC19A1, FOLR2 | MEN1 1700/4885KMT2A 2105/4885FAAH 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.