Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.64 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.46 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.46 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22917089 | 1.00 | FAAH (0.64) | FAAHKDM4CKDM4APHF8KDM2A | |
| SCHEMBL23581448 | 1.00 | FAAH (0.64) | FAAHKDM4CKDM4APHF8KDM2A | |
| SCHEMBL18772640 | 0.98 | FAAH (0.61) | FAAHKDM4CKDM4APHF8KDM2A | |
| SCHEMBL14552886 | 0.92 | FAAH (0.57) | FAAHMEN1KMT2ACYP1A2POLB | |
| SCHEMBL425951 | 0.86 | ALDH1A1 (0.55) | FAAHKDM4CKDM4APHF8KDM2A | |
| SCHEMBL2540536 | 0.86 | KDM4C (0.47) | FAAHKDM4CKDM4APHF8KDM2A | |
| SCHEMBL10064157 | 0.85 | FAAH (0.86) | FAAHMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL13268369 | 0.85 | FAAH (0.86) | FAAHMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL17670549 | 0.85 | FAAH (0.60) | FAAHMEN1KMT2AMAPK1CAPN1 | |
| SCHEMBL20035023 | 0.85 | CASP2 (0.48) | FAAHMEN1KMT2ATSHRCAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116920-A1 | PENTA- FUSED HEXA-HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| WO-2018013525-A1 | NUCLEIC ACID CONJUGATES AND USES THEREOF | TRANSLATE BIO MA, INC. (US) | 2018-01-18 | — | — | WO | disclosed |