Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 13/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19782985 | 0.93 | DHODH (0.51) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19782993 | 0.92 | DHODH (0.47) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL29601738 | 0.85 | DHODH (0.50) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27039803 | 0.85 | DHODH (0.50) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19783118 | 0.84 | DHODH (0.48) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15993345 | 0.84 | DHODH (0.58) | DHODHMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL15993447 | 0.82 | DHODH (0.54) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL15993448 | 0.81 | DHODH (0.53) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19783106 | 0.81 | DHODH (0.53) | DHODHMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19783114 | 0.81 | ALDH1A1 (0.65) | DHODHMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913734-B2 | Substituted aminothiazoles | BARUCH S. BLUMBERG INSTITUTE | 2021-02-09 | — | — | US | disclosed |
| US-20190241552-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE | 2019-08-08 | — | — | US | disclosed |
| WO-2018013508-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913734-B2 | Substituted aminothiazoles | ABAT, AADAT, BCAT1 | DHODH 329/4885MAPT 307/4885MEN1 2492/4885 |
| US-20190241552-A1 | SUBSTITUTED AMINOTHIAZOLES | ABAT, AADAT, BCAT1 | DHODH 329/4885MAPT 307/4885MEN1 2492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.