Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | ADAMTS13 | Q76LX8 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM6A | O15550 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4B | O94953 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783019 | 0.80 | ALDH1A1 (0.42) | LMNAALDH1A1KDM4EAPOBEC3GMAPT | |
| SCHEMBL19782983 | 0.78 | MAPT (0.45) | LMNAALDH1A1KDM4EAPOBEC3GMAPT | |
| SCHEMBL19782387 | 0.76 | MAPT (0.36) | LMNAALDH1A1KDM4EAPOBEC3GMAPT | |
| SCHEMBL19783107 | 0.70 | ALDH1A1 (0.47) | LMNAALDH1A1KDM4EAPOBEC3GMAPT | |
| SCHEMBL19783021 | 0.68 | ALDH1A1 (0.49) | LMNAALDH1A1KDM4EAPOBEC3GMAPT | |
| SCHEMBL19783018 | 0.66 | ADAMTS5 (0.50) | ALDH1A1KDM4EAPOBEC3GMAPTGAA | |
| SCHEMBL15993205 | 0.65 | ALDH1A1 (0.41) | LMNAALDH1A1KDM4EAPOBEC3GMAPT | |
| SCHEMBL21221232 | 0.65 | NPC1 (0.47) | LMNAALDH1A1KDM4EAPOBEC3GMAPT | |
| SCHEMBL19782984 | 0.63 | ADAMTS5 (0.52) | ALDH1A1KDM4EAPOBEC3GMAPTGAA | |
| SCHEMBL19783020 | 0.62 | ADAMTS5 (0.36) | LMNAALDH1A1KDM4EAPOBEC3GMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013508-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE (US) | 2018-01-18 | — | — | WO | disclosed |