Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22172057 | 0.90 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGDTLR8L3MBTL1 | |
| SCHEMBL19783288 | 0.86 | TLR8 (0.35) | ESR2TLR8ADORA3 | |
| SCHEMBL21422303 | 0.85 | TLR8 (0.39) | ALDH1A1HPGDESR2TLR8CACNA2D1 | |
| SCHEMBL21422279 | 0.77 | ALDH1A1 (0.39) | ALDH1A1KDM4EESR2TLR8L3MBTL1 | |
| SCHEMBL19783974 | 0.72 | POLB (0.38) | ALDH1A1KDM4EESR2TLR8TP53 | |
| SCHEMBL19783856 | 0.72 | ESR2 (0.41) | ALDH1A1KDM4EESR2TLR8ADORA3 | |
| SCHEMBL19784122 | 0.71 | GRIN1 (0.39) | ALDH1A1KDM4EHPGDTLR8TP53 | |
| SCHEMBL19783865 | 0.71 | TLR8 (0.39) | ALDH1A1HPGDTLR8CACNA2D1HDAC1 | |
| SCHEMBL19784119 | 0.70 | USP2 (0.39) | ALDH1A1TLR8MEN1KMT2A | |
| SCHEMBL19784121 | 0.70 | HIF1A (0.39) | ALDH1A1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484877-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2020-07-01 | — | — | EP | disclosed |
| WO-2018011111-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |