Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783296 | 0.86 | ALDH1A1 (0.38) | TLR8ESR2ADORA3 | |
| SCHEMBL21422303 | 0.85 | TLR8 (0.39) | TLR8MAT2AP2RX7ESR2CYP11B2 | |
| SCHEMBL22172057 | 0.81 | ALDH1A1 (0.34) | TLR8MAT2AP2RX7 | |
| SCHEMBL19783295 | 0.76 | TLR8 (0.39) | TLR8MAT2AESR2IRAK4DGAT1 | |
| SCHEMBL21422263 | 0.76 | TLR8 (0.37) | TLR8MAT2AESR2IRAK4DGAT1 | |
| SCHEMBL19783867 | 0.72 | CYP11B2 (0.37) | TLR8MAT2AESR2IRAK4DGAT1 | |
| SCHEMBL19783865 | 0.71 | TLR8 (0.39) | TLR8MAT2AP2RX7CYP11B2 | |
| SCHEMBL19783990 | 0.69 | TLR8 (0.44) | TLR8MAT2AESR2CYP11B2PTGS2 | |
| SCHEMBL19783856 | 0.68 | ESR2 (0.41) | TLR8MAT2AESR2ADORA3 | |
| SCHEMBL17811752 | 0.68 | MAT2A (0.39) | TLR8MAT2AESR2IRAK4CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018011111-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |