Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | SNRNP200 | O75643 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAD1 | O60671 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19783976 | 0.87 | ADORA2A (0.39) | ESR2CYP11B2MAPTKMT2ATLR8 | |
| SCHEMBL19783977 | 0.85 | ESR2 (0.41) | POLBESR2CYP11B2MDM2MAPT | |
| SCHEMBL19783867 | 0.85 | CYP11B2 (0.37) | ESR2CYP11B2TLR8ADORA2ACYP2A6 | |
| SCHEMBL19783973 | 0.84 | MAT2A (0.36) | ESR2CYP11B2ALDH1A1KDM4ETLR8 | |
| SCHEMBL19783854 | 0.82 | TLR8 (0.38) | POLBESR2CYP11B2MAPTALDH1A1 | |
| SCHEMBL21422259 | 0.82 | ESR2 (0.39) | ESR2CYP11B2MAPTALDH1A1TLR8 | |
| SCHEMBL19783858 | 0.82 | TLR8 (0.45) | ESR2CYP11B2TLR8ADORA2ACYP2A6 | |
| SCHEMBL21422279 | 0.82 | ALDH1A1 (0.39) | ESR2KDM4CCYP11B2MAPTALDH1A1 | |
| SCHEMBL11853019 | 0.75 | TP53 (0.52) | TP53MDM2MAPTALDH1A1KMT2A | |
| SCHEMBL19784121 | 0.74 | HIF1A (0.39) | CYP11B2ALDH1A1TLR8CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484877-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-20190297887-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-03 | — | — | US | disclosed |
| WO-2018011111-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190297887-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | DDT, BCHE, ACHE | POLB 3684/4885ESR2 3670/4885KDM4C 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.