Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19784370 | 0.92 | ADRB2 (0.50) | ADRB2CHRM3CHRM4 | |
| SCHEMBL19784600 | 0.81 | ADRB2 (0.40) | ADRB2CHRM3 | |
| SCHEMBL22839974 | 0.81 | ADRB2 (0.40) | ADRB2CHRM3 | |
| SCHEMBL22839873 | 0.80 | ADRB2 (0.56) | ADRB2CHRM3CHRM4 | |
| SCHEMBL22839981 | 0.78 | ADRB2 (0.46) | ADRB2CHRM3 | |
| SCHEMBL22839902 | 0.78 | ADRB2 (0.37) | ADRB2CHRM3 | |
| SCHEMBL22839907 | 0.77 | ADRB2 (0.45) | ADRB2CHRM3 | |
| SCHEMBL24404548 | 0.77 | ADRB2 (0.52) | ADRB2CHRM3 | |
| SCHEMBL22839800 | 0.77 | ADRB2 (0.49) | ADRB2CHRM3MEN1KMT2A | |
| SCHEMBL22839971 | 0.77 | ADRB2 (0.49) | ADRB2CHRM3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484879-B1 | HYDROXYQUINOLINONE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-12-30 | — | — | EP | disclosed |