⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57181 | 0.78 | KIF11 (0.32) | — | |
| SCHEMBL3680410 | 0.73 | — | — | |
| SCHEMBL56325 | 0.71 | NFKB1 (0.35) | — | |
| SCHEMBL16892641 | 0.70 | DNM1 (0.38) | — | |
| SCHEMBL302858 | 0.70 | CYP1A2 (0.31) | — | |
| SCHEMBL1862073 | 0.67 | DNM1 (0.33) | — | |
| SCHEMBL8764550 | 0.65 | — | — | |
| SCHEMBL1041602 | 0.65 | ODC1 (0.32) | — | |
| SCHEMBL1845795 | 0.64 | DNM1 (0.35) | — | |
| SCHEMBL18095414 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343329-B1 | AMINO ACID GROUP-MODIFIED ORGANOPOLYSILOXANE AND SILANE, AMINO ACID GROUP-CONTAINING COMPOUND, AND PRODUCTION METHOD THEREOF | SHINETSU CHEMICAL CO (JP) | 2014-03-19 | — | — | EP | disclosed |
| US-20130096340-A1 | AMINO ACID GROUP-MODIFIED ORGANOPOLYSILOXANE AND SILANE, AMINO ACID GROUP-CONTAINING COMPOUND, AND PRODUCTION METHOD THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-04-18 | — | — | US | disclosed |
| US-8394980-B2 | Amino acid group-modified organopolysiloxane and silane, amino acid group-containing compound, and production method thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2013-03-12 | — | — | US | disclosed |
| US-8338630-B2 | Amino acid group-modified organopolysiloxane and silane, amino acid group-containing compound, and production method thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20120309983-A1 | AMINO ACID GROUP-MODIFIED ORGANOPOLYSILOXANE AND SILANE, AMINO ACID GROUP-CONTAINING COMPOUND, AND PRODUCTION METHOD THEREOF | MORIYA HIROYUKI (JP) | 2012-12-06 | — | — | US | disclosed |
| EP-2343329-A1 | Amino acid group-modified organopolysiloxane and silane, amino acid group-containing compound, and production method thereof | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-07-13 | — | — | EP | disclosed |
| US-20110144369-A1 | AMINO ACID GROUP-MODIFIED ORGANOPOLYSILOXANE AND SILANE, AMINO ACID GROUP-CONTAINING COMPOUND, AND PRODUCTION METHOD THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-06-16 | — | — | US | disclosed |
| EP-1068213-A4 | NOVEL AMINOORGANOFUNCTIONALSILOXANES | ARCHIMICA FLORIDA INC (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-1068213-A1 | NOVEL AMINOORGANOFUNCTIONALSILOXANES | ARCHIMICA (FLORIDA), Inc. (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6002038-A | Fluorosilicone compounds in the form of oil and use of same in cosmetics | L'OREAL (FR) | 1999-12-14 | — | — | US | disclosed |
| WO-1999038872-A1 | NOVEL AMINOORGANOFUNCTIONALSILOXANES | ARCHIMICA (FLORIDA) INC. (US) | 1999-08-05 | — | — | WO | disclosed |
| US-5892084-A | Aminoorganofunctionalsiloxanes | PCR, INC. (US) | 1999-04-06 | — | — | US | disclosed |