SCHEMBL19784886

SCHEMBL19784886

CCCc1nc(C)n(C)n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.50
TDP2 O95551 2/20 0.50
KDM4E B2RXH2 1/20 0.50
NPC1 O15118 1/20 0.50
ABL1 P00519 1/20 0.50
POLB P06746 1/20 0.50
MAPT P10636 1/20 0.50
THRB P10828 1/20 0.50
MPI P34949 1/20 0.50
HTT P42858 1/20 0.50
RAB9A P51151 1/20 0.50
DUSP3 P51452 1/20 0.50
GALK1 P51570 1/20 0.50
BLM P54132 1/20 0.50
CASP9 P55211 1/20 0.50
CASP6 P55212 1/20 0.50
RIN1 Q13671 1/20 0.50
CASP8 Q14790 1/20 0.50
PDIA6 Q15084 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18673167 0.81
SCHEMBL18965320 0.80 KDM4E (0.34) RECQLTDP2KDM4ENPC1ABL1
SCHEMBL13246634 0.74
SCHEMBL4782922 0.74
Hydrochloric Acid SCHEMBL4786213 0.73 GAA (0.34)
SCHEMBL16307583 0.71 HTR7 (0.31)
SCHEMBL21889053 0.69 SIGMAR1 (0.43) RECQLTDP2KDM4ENPC1ABL1
SCHEMBL15032586 0.68 TDP2 (1.00) RECQLTDP2KDM4ENPC1ABL1
SCHEMBL12759741 0.67 USP2 (0.47) RECQLTDP2KDM4ENPC1ABL1
SCHEMBL11811150 0.65 HRH4 (0.38) RECQLTDP2KDM4ENPC1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210792-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING OXIME GROUP, AGRICULTURAL/HORTICULTURAL HERBICIDE CONTAINING SAID COMPOUND, AND USE OF BOTH OF FOREGOING 日本農薬株式会社 2023-11-02 WO disclosed
EP-3626699-B1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2023-07-12 EP disclosed
US-20210198220-A1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2021-07-01 US disclosed
US-11001563-B2 SSAO inhibitor SHANDONG DANHONG PHARMACEUTICAL CO LTD (CN) 2021-05-11 US disclosed
US-20200115352-A1 SSAO INHIBITOR SHANDONG DANHONG PHARMACEUTICAL CO., LTD. 2020-04-16 US disclosed
EP-3626699-A1 SSAO INHIBITOR Shandong Danhong Pharmaceutical Co., Ltd. (CN) 2020-03-25 EP disclosed
US-10323181-B2 Composition containing phosphorescent compound and light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-06-18 US disclosed
US-20180016492-A1 COMPOSITION AND LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11001563-B2 SSAO inhibitor SSB, ASAH2, AOX1 RECQL 1147/4885TDP2 1964/4885KDM4E 2172/4885
US-20210198220-A1 SSAO INHIBITOR SSB, ASAH2, AOX1 RECQL 1147/4885TDP2 1964/4885KDM4E 2172/4885
US-20200115352-A1 SSAO INHIBITOR SSB, ASAH2, AOX1 RECQL 1147/4885TDP2 1964/4885KDM4E 2172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.