SCHEMBL19785204

SCHEMBL19785204

C[SiH](C)c1ccc(-c2ccc(Nc3ccc(-c4ccc([SiH](C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.38
TDP1 Q9NUW8 3/20 0.38
HSD17B10 Q99714 3/20 0.38
ALDH1A1 P00352 3/20 0.38
ALOX12 P18054 3/20 0.38
MAPK1 P28482 2/20 0.38
ALOX15 P16050 2/20 0.38
TSHR P16473 2/20 0.38
PTGS1 P23219 1/20 0.38
SLC6A2 P23975 1/20 0.38
PTGS2 P35354 1/20 0.38
HTR2B P41595 1/20 0.38
MAPT P10636 3/20 0.37
THRB P10828 2/20 0.37
RECQL P46063 2/20 0.37
GAA P10253 2/20 0.37
KDM4E B2RXH2 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20077177 0.92 ALDH1A1 (0.43) L3MBTL1TDP1HSD17B10ALDH1A1ALOX12
SCHEMBL19785202 0.86 SCN5A (0.31)
SCHEMBL2579397 0.84 ALDH1A1 (0.32) TDP1ALDH1A1CYP3A4
SCHEMBL20077077 0.83 HPGD (0.56) L3MBTL1TDP1ALDH1A1MAPK1MAPT
SCHEMBL2438805 0.74
SCHEMBL148576 0.74
SCHEMBL16075803 0.74 ALDH1A1 (0.50) TDP1HSD17B10ALDH1A1MAPK1PTGS2
SCHEMBL10098397 0.74 ACHE (0.44) TDP1HSD17B10ALDH1A1ALOX15GAA
SCHEMBL19785007 0.72 CYP3A4 (0.58) TDP1HSD17B10ALDH1A1MAPK1ALOX15
SCHEMBL5918700 0.70 HPGD (0.67) L3MBTL1TDP1HSD17B10ALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10629830-B2 Organic electroluminescent device SAMSUNG DISPLAY CO., LTD. (KR) 2020-04-21 US disclosed
US-20180019416-A1 ORGANIC ELECTROLUMINESCENT DEVICE SAMSUNG DISPLAY CO LTD (KR) 2018-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019416-A1 ORGANIC ELECTROLUMINESCENT DEVICE ARL1, RIF1, LARS1 L3MBTL1 449/4885TDP1 3724/4885HSD17B10 2081/4885
US-10629830-B2 Organic electroluminescent device ARL1, RIF1, LARS1 L3MBTL1 449/4885TDP1 3724/4885HSD17B10 2081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.