SCHEMBL19785650

SCHEMBL19785650

C=CCSS/C=C\CSCc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.40
MAOB P27338 1/20 0.35
CYP2C19 P33261 3/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 2/20 0.33
PKM P14618 1/20 0.33
GAA P10253 1/20 0.31
TRPA1 O75762 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAPK1 P28482 1/20 0.30
IDO1 P14902 1/20 0.30
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21189957 1.00 PTGS2 (0.40) PTGS2MAOBCYP2C19CYP1A2CYP2D6
SCHEMBL21189954 0.87 ALOX5 (0.35) PTGS2MAOBCYP2C19CYP1A2CYP2D6
SCHEMBL21189912 0.86 MAOB (0.40) MAOBCYP2C19CYP1A2CYP2D6CYP2C9
SCHEMBL21189959 0.86 MAOB (0.40) MAOBCYP2C19CYP1A2CYP2D6CYP2C9
SCHEMBL23796535 0.81 IDO1 (0.38) PTGS2L3MBTL1IDO1
SCHEMBL23796537 0.81 IDO1 (0.38) PTGS2L3MBTL1IDO1
SCHEMBL1121965 0.80 CYP2C19 (0.44) MAOBCYP2C19CYP1A2CYP2D6CYP2C9
SCHEMBL21189958 0.79 CYP2C19 (0.37) MAOBCYP2C19CYP1A2CYP2D6CYP2C9
SCHEMBL21190164 0.79 CYP2C19 (0.37) MAOBCYP2C19CYP1A2CYP2D6CYP2C9
SCHEMBL21190098 0.78 LMNA (0.36) MAOBCYP2C19ALDH1A1PKMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019143143-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROBLASTOMA OR RHEUMATOID ARTHRITIS 숙명여자대학교 산학협력단 2019-07-25 WO disclosed
WO-2019143142-A1 NOVEL PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING GLIOBLASTOMA 숙명여자대학교 산학협력단 2019-07-25 WO disclosed
WO-2018012947-A1 NOVEL ORGANIC SULFUR COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER OR AN INFLAMMATORY DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT 숙명여자대학교 산학협력단 2018-01-18 WO disclosed