Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21190121 | 1.00 | LMNA (0.36) | LMNAMAPTPOLBTSHRRAB9A | |
| SCHEMBL21189959 | 0.91 | MAOB (0.40) | LMNAPOLBRAB9AALDH1A1IDO1 | |
| SCHEMBL21189912 | 0.91 | MAOB (0.40) | LMNAPOLBRAB9AALDH1A1IDO1 | |
| SCHEMBL19786100 | 0.85 | ALDH1A1 (0.39) | LMNAMAPTPOLBRAB9AALDH1A1 | |
| SCHEMBL19785863 | 0.84 | ALDH1A1 (0.40) | LMNAMAPTRAB9AEPHX1ALDH1A1 | |
| SCHEMBL19786064 | 0.84 | ALDH1A1 (0.40) | LMNAMAPTRAB9AEPHX1ALDH1A1 | |
| SCHEMBL21189907 | 0.82 | SMN1; SMN2 (0.35) | ALDH1A1TP53KMT2AIDO1HPGD | |
| SCHEMBL21189955 | 0.82 | SMN1; SMN2 (0.35) | ALDH1A1TP53KMT2AIDO1HPGD | |
| SCHEMBL21190016 | 0.81 | LTA4H (0.46) | LMNAMAPTTSHRRAB9AEPHX1 | |
| SCHEMBL21189913 | 0.81 | LTA4H (0.46) | LMNAMAPTTSHRRAB9AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143143-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROBLASTOMA OR RHEUMATOID ARTHRITIS | 숙명여자대학교 산학협력단 | 2019-07-25 | — | — | WO | disclosed |
| WO-2019143142-A1 | NOVEL PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING GLIOBLASTOMA | 숙명여자대학교 산학협력단 | 2019-07-25 | — | — | WO | disclosed |