Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19786121 | 1.00 | MTNR1A (0.43) | MTNR1AMTNR1BMAOAMAOBALOX15 | |
| SCHEMBL19786117 | 0.84 | MTNR1A (0.40) | MTNR1AMTNR1BMAOAMAOBTERT | |
| SCHEMBL19785866 | 0.84 | MTNR1A (0.40) | MTNR1AMTNR1BMAOAMAOBTERT | |
| SCHEMBL19786005 | 0.83 | ALDH1A1 (0.38) | MTNR1AMTNR1BMAOAMAOBMAPK1 | |
| SCHEMBL19785903 | 0.83 | ALDH1A1 (0.38) | MTNR1AMTNR1BMAOAMAOBMAPK1 | |
| SCHEMBL21189911 | 0.82 | MAOB (0.43) | MTNR1AMTNR1BMAOAMAOBNPC1 | |
| SCHEMBL21189901 | 0.82 | MAOB (0.43) | MTNR1AMTNR1BMAOAMAOBNPC1 | |
| SCHEMBL19785898 | 0.80 | MAOB (0.46) | MTNR1AMTNR1BMAOAMAOBDHFR | |
| SCHEMBL21190025 | 0.80 | ALDH1A1 (0.41) | MTNR1AMTNR1BMAOAMAOBMAPK1 | |
| SCHEMBL19785878 | 0.80 | ALDH1A1 (0.41) | MTNR1AMTNR1BMAOAMAOBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143143-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROBLASTOMA OR RHEUMATOID ARTHRITIS | 숙명여자대학교 산학협력단 | 2019-07-25 | — | — | WO | disclosed |
| WO-2018012947-A1 | NOVEL ORGANIC SULFUR COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER OR AN INFLAMMATORY DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT | 숙명여자대학교 산학협력단 | 2018-01-18 | — | — | WO | disclosed |