Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | AGXT | P21549 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19786117 | 1.00 | MTNR1A (0.40) | MTNR1AMTNR1BUSP2ALDH1A1MAOB | |
| SCHEMBL21191983 | 0.84 | MTNR1A (0.49) | MTNR1AMTNR1BUSP2ALDH1A1MAOB | |
| SCHEMBL19786070 | 0.84 | MTNR1A (0.43) | MTNR1AMTNR1BMAOBMAOATERT | |
| SCHEMBL19786121 | 0.84 | MTNR1A (0.43) | MTNR1AMTNR1BMAOBMAOATERT | |
| SCHEMBL19786023 | 0.83 | ALDH1A1 (0.40) | MTNR1AMTNR1BALDH1A1MAOBMAOA | |
| SCHEMBL19786083 | 0.83 | ALDH1A1 (0.40) | MTNR1AMTNR1BALDH1A1MAOBMAOA | |
| SCHEMBL21189911 | 0.82 | MAOB (0.43) | MTNR1AMTNR1BALDH1A1MAOBMAOA | |
| SCHEMBL21189901 | 0.82 | MAOB (0.43) | MTNR1AMTNR1BALDH1A1MAOBMAOA | |
| SCHEMBL19785898 | 0.80 | MAOB (0.46) | MTNR1AMTNR1BMAOBMAOADHFR | |
| SCHEMBL21190019 | 0.79 | MAOB (0.47) | MTNR1AMTNR1BMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143143-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NEUROBLASTOMA OR RHEUMATOID ARTHRITIS | 숙명여자대학교 산학협력단 | 2019-07-25 | — | — | WO | disclosed |
| WO-2019143142-A1 | NOVEL PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING GLIOBLASTOMA | 숙명여자대학교 산학협력단 | 2019-07-25 | — | — | WO | disclosed |
| WO-2018012947-A1 | NOVEL ORGANIC SULFUR COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER OR AN INFLAMMATORY DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT | 숙명여자대학교 산학협력단 | 2018-01-18 | — | — | WO | disclosed |