SCHEMBL19786100

SCHEMBL19786100

Cc1ccc(CSS/C=C\CSCc2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
MAPT P10636 2/20 0.39
LMNA P02545 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HTT P42858 1/20 0.39
BCHE P06276 1/20 0.39
ACHE P22303 1/20 0.39
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
POLB P06746 4/20 0.36
HPGD P15428 3/20 0.36
CNR2 P34972 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
RECQL P46063 1/20 0.34
SCN5A Q14524 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21189912 0.91 MAOB (0.40) ALDH1A1LMNANPC1RAB9APOLB
SCHEMBL21189959 0.91 MAOB (0.40) ALDH1A1LMNANPC1RAB9APOLB
SCHEMBL21190098 0.85 LMNA (0.36) ALDH1A1MAPTLMNAKMT2ARAB9A
SCHEMBL21190121 0.85 LMNA (0.36) ALDH1A1MAPTLMNAKMT2ARAB9A
SCHEMBL21190016 0.84 LTA4H (0.46) ALDH1A1MAPTLMNAHTTRAB9A
SCHEMBL21189913 0.84 LTA4H (0.46) ALDH1A1MAPTLMNAHTTRAB9A
SCHEMBL19786067 0.84 HPGD (0.40) ALDH1A1MAPTMEN1KMT2AHTT
SCHEMBL21189958 0.80 CYP2C19 (0.37) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL21190164 0.80 CYP2C19 (0.37) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL21189954 0.78 ALOX5 (0.35) ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018012947-A1 NOVEL ORGANIC SULFUR COMPOUND, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING CANCER OR AN INFLAMMATORY DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT 숙명여자대학교 산학협력단 2018-01-18 WO disclosed