Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
| ▸ | STAT1 | P42224 | 1/20 | 0.56 |
| ▸ | TERT | O14746 | 2/20 | 0.37 |
| ▸ | TOP1 | P11387 | 2/20 | 0.36 |
| ▸ | CYCS | P99999 | 3/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30426808 | 1.00 | STAT3 (0.56) | STAT3STAT1TERTTOP1CYCS | |
| SCHEMBL29738339 | 0.97 | STAT3 (0.58) | STAT3STAT1TERTTOP1CYCS | |
| SCHEMBL31127549 | 0.95 | STAT3 (0.57) | STAT3STAT1TERTTOP1CYCS | |
| SCHEMBL1290623 | 0.94 | STAT3 (0.56) | STAT3STAT1TERTTOP1CYCS | |
| SCHEMBL3005847 | 0.93 | STAT3 (0.50) | STAT3STAT1TERTTOP1CYCS | |
| Hydrochloric Acid SCHEMBL2963616 | 0.92 | STAT3 (0.49) | STAT3STAT1TERTTOP1CYCS | |
| Hydrochloric Acid SCHEMBL5596534 | 0.92 | STAT3 (0.53) | STAT3STAT1TERTTOP1 | |
| SCHEMBL19206150 | 0.86 | STAT3 (0.53) | STAT3STAT1TERT | |
| SCHEMBL29582816 | 0.84 | TERT (0.47) | TERTTOP1CYCSENPP2 | |
| SCHEMBL29353372 | 0.84 | TERT (0.47) | TERTTOP1CYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011081651-A1 | METHODS AND COMPOSITIONS COMPRISING MACROCYCLES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-07-07 | — | — | WO | disclosed |
| US-20110144324-A1 | METHODS AND COMPOSITIONS COMPRISING MACROCYCLES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2011-06-16 | — | — | US | disclosed |
| US-7518905-B2 | High density memory device | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-04-14 | — | — | US | disclosed |
| US-20060209587-A1 | High density memory device | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-09-21 | — | — | US | disclosed |
| US-7061791-B2 | High density molecular memory device | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-06-13 | — | — | US | disclosed |
| US-7042755-B1 | High density non-volatile memory device | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-05-09 | — | — | US | disclosed |
| US-20050041494-A1 | High density non-volatile memory device | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA AND NORTH CAROLINA STATE UNIVERSITY | 2005-02-24 | — | — | US | disclosed |
| US-6657884-B2 | High density non-volatile memory device | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-12-02 | — | — | US | disclosed |
| US-20020154535-A1 | High density non-volatile memory device | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER | 2002-10-24 | — | — | US | disclosed |
| US-6381169-B1 | FIXED ELECTRODES COUPLING TO STORAGE MEDIA | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-04-30 | — | — | US | disclosed |
| US-6208553-B1 | High density non-volatile memory device incorporating thiol-derivatized porphyrins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110144324-A1 | METHODS AND COMPOSITIONS COMPRISING MACROCYCLES | PMS2, TERT, C5 | STAT3 4451/4885STAT1 4789/4885TERT 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.