Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 4/20 | 0.33 |
| ▸ | CYCS | P99999 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30426808 | 0.92 | STAT3 (0.56) | STAT3STAT1TOP1TERTCYCS | |
| SCHEMBL1978627 | 0.92 | STAT3 (0.56) | STAT3STAT1TOP1TERTCYCS | |
| SCHEMBL29738339 | 0.89 | STAT3 (0.58) | STAT3STAT1TOP1TERTCYCS | |
| SCHEMBL31127549 | 0.88 | STAT3 (0.57) | STAT3STAT1TOP1TERTCYCS | |
| Hydrochloric Acid SCHEMBL5596534 | 0.87 | STAT3 (0.53) | STAT3STAT1TOP1TERT | |
| SCHEMBL1290623 | 0.87 | STAT3 (0.56) | STAT3STAT1TOP1TERTCYCS | |
| SCHEMBL3005847 | 0.86 | STAT3 (0.50) | STAT3STAT1TOP1TERTCYCS | |
| SCHEMBL19206150 | 0.79 | STAT3 (0.53) | STAT3STAT1TERT | |
| Hydrochloric Acid SCHEMBL21493256 | 0.78 | TOP1 (0.45) | TOP1TERTCYCS | |
| Hydrochloric Acid SCHEMBL6865971 | 0.78 | TOP1 (0.45) | TOP1TERTCYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100291670-A1 | Method for Detecting Candida on Skin | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2010-11-18 | — | — | US | disclosed |
| US-7763442-B2 | Method for detecting candida on skin | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2010-07-27 | — | — | US | disclosed |
| US-7531319-B2 | Array for rapid detection of a microorganism | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2009-05-12 | — | — | US | disclosed |
| US-20080145316-A1 | Skin coating with microbial indicator | KIMBERLY-CLARK WORLDWIDE, INC. | 2008-06-19 | — | — | US | disclosed |
| US-20080057533-A1 | Array for rapid detection of a microorganism | KIMBERLY-CLARK WORLDWIDE, INC. | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080145316-A1 | Skin coating with microbial indicator | CUTA, S100A8, STING1 | STAT3 1898/4885STAT1 1223/4885TOP1 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.