Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14715673 | 0.85 | TSHR (0.42) | LMNANAAATSHRALDH1A1 | |
| SCHEMBL27982814 | 0.85 | NAAA (0.44) | NAAATSHRALDH1A1CYP3A4EPHX1 | |
| SCHEMBL8421539 | 0.85 | NAAA (0.44) | NAAATSHRALDH1A1CYP3A4EPHX1 | |
| SCHEMBL6897000 | 0.84 | LMNA (0.55) | LMNANAAATSHRALDH1A1EPHX1 | |
| SCHEMBL27781760 | 0.82 | RARB (0.37) | LMNANAAATSHREPHX1 | |
| SCHEMBL10087932 | 0.82 | LMNA (0.52) | LMNANAAATSHRALDH1A1CYP3A4 | |
| SCHEMBL29728734 | 0.82 | TSHR (0.36) | LMNATSHRALDH1A1 | |
| SCHEMBL18669142 | 0.82 | ACHE (0.41) | LMNANAAATSHRALDH1A1ACHE | |
| SCHEMBL13133071 | 0.80 | TSHR (0.46) | LMNATSHRALDH1A1 | |
| SCHEMBL9110412 | 0.80 | TSHR (0.34) | LMNANAAATSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013886-A1 | CAST URETHANES MADE FROM LOW FREE MONOMER PREPOLYMER WITH POLYCARBONATE BACKBONE | LANXESS SOLUTIONS US INC. (US) | 2018-01-18 | — | — | WO | disclosed |