Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.60 |
| ▸ | HRH2 | P25021 | 15/20 | 0.59 |
| ▸ | HRH1 | P35367 | 15/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1978693 | 1.00 | HRH3 (0.60) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL1978690 | 1.00 | HRH3 (0.60) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL1981213 | 0.86 | HRH3 (0.45) | HRH3HRH2HRH1 | |
| SCHEMBL1981211 | 0.86 | HRH3 (0.45) | HRH3HRH2HRH1 | |
| SCHEMBL1981215 | 0.80 | ALDH1A1 (0.43) | HRH3HRH2HRH1 | |
| SCHEMBL1976731 | 0.79 | KDM1A (0.49) | HRH3MEN1 | |
| SCHEMBL1976733 | 0.79 | KDM1A (0.49) | HRH3MEN1 | |
| SCHEMBL1976735 | 0.79 | KDM1A (0.49) | HRH3MEN1 | |
| SCHEMBL1978872 | 0.78 | HRH3 (0.57) | HRH3HRH2HRH1MEN1 | |
| SCHEMBL1978869 | 0.78 | HRH3 (0.57) | HRH3HRH2HRH1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283245-A1 | AZABICYCLO[3.1.0]HEX-2-YL COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2012-11-08 | — | — | US | disclosed |
| EP-2509947-A1 | AZABICYCLO[3.1.0]HEX-2-YL DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011070253-A1 | AZABICYCLO[3.1.0]HEX-2-YL DERIVATIVES, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2011-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283245-A1 | AZABICYCLO[3.1.0]HEX-2-YL COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | AGER, AZI2, HTT | HRH3 1708/4885HRH2 2436/4885HRH1 1942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.