Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 3/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | NQO2 | P16083 | 2/20 | 0.53 |
| ▸ | AHR | P35869 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12028758 | 0.81 | KDM4E (0.59) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL678598 | 0.81 | KDM4E (0.59) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL14950253 | 0.79 | RELA (0.81) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL699457 | 0.79 | RELA (0.81) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL631998 | 0.79 | RELA (0.81) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL13790336 | 0.79 | RELA (0.81) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL699458 | 0.79 | RELA (0.81) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL4881152 | 0.79 | RELA (0.81) | NFE2L2KDM4ECYP3A4LMNATP53 | |
| SCHEMBL28891539 | 0.79 | CYP1A1 (0.64) | KDM4EALDH1A1CYP1A2CYP1A1CYP1B1 | |
| SCHEMBL8059285 | 0.78 | ALDH1A1 (0.52) | NFE2L2KDM4ECYP3A4LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11020730-B2 | Halogen-containing metathesis catalysts and methods thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-06-01 | — | — | US | disclosed |
| US-20190314799-A1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-10-17 | — | — | US | disclosed |
| WO-2018013943-A1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190314799-A1 | HALOGEN-CONTAINING METATHESIS CATALYSTS AND METHODS THEREOF | ZRANB2, SLC39A3, ZCCHC8 | NFE2L2 562/4885KDM4E 3878/4885CYP3A4 698/4885 |
| US-11020730-B2 | Halogen-containing metathesis catalysts and methods thereof | ZRANB2, SLC39A3, ZCCHC8 | NFE2L2 562/4885KDM4E 3878/4885CYP3A4 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.