Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 17/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23613545 | 0.79 | ACLY (0.41) | RIPK1TDP1 | |
| SCHEMBL5264333 | 0.77 | ALDH1A1 (0.40) | RIPK1ELANEMEN1KMT2ATDP1 | |
| SCHEMBL8962266 | 0.77 | RIPK1 (0.38) | RIPK1MEN1KMT2A | |
| SCHEMBL23469843 | 0.76 | ALDH1A1 (0.38) | RIPK1ALDH1A1 | |
| SCHEMBL26351138 | 0.74 | DNM1 (0.37) | RIPK1ALDH1A1 | |
| SCHEMBL23613549 | 0.72 | PPARA (0.32) | TDP1 | |
| SCHEMBL23613340 | 0.72 | ACACB (0.46) | MEN1KMT2A | |
| SCHEMBL17615113 | 0.71 | NPC1 (0.31) | — | |
| SCHEMBL14010563 | 0.71 | — | — | |
| SCHEMBL276239 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9872918-B2 | Hydroxyl-polymer-drug-protein conjugates | MERSANA THERAPEUTICS, INC. (US) | 2018-01-23 | — | — | US | disclosed |