Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.33 |
| ▸ | PPARG | P37231 | 5/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19789587 | 0.88 | THRB (0.39) | THRBITGB3ITGA2BHPGDTSHR | |
| SCHEMBL14907498 | 0.86 | FAAH (0.39) | FAAHTHRBHPGDTSHR | |
| SCHEMBL14907444 | 0.86 | FAAH (0.39) | FAAHTHRBHPGDTSHR | |
| SCHEMBL14907552 | 0.82 | THRB (0.47) | THRBITGB3ITGA2BHPGDTSHR | |
| SCHEMBL14088541 | 0.82 | FAAH (0.40) | FAAHTHRBITGB3ITGA2BTSHR | |
| SCHEMBL19789602 | 0.79 | TSHR (0.43) | FAAHTHRBHPGDTSHR | |
| SCHEMBL14088542 | 0.79 | FAAH (0.41) | FAAHTHRBITGB3ITGA2BPPARG | |
| SCHEMBL14907440 | 0.79 | RARB (0.43) | THRBITGB3ITGA2BHPGDTSHR | |
| SCHEMBL14907487 | 0.76 | THRB (0.45) | THRBITGB3ITGA2BHPGDTSHR | |
| SCHEMBL14907500 | 0.74 | THRB (0.46) | FAAHTHRBHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |