Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14907552 | 0.89 | THRB (0.47) | THRBITGB3ITGA2BHPGDTSHR | |
| SCHEMBL19789528 | 0.88 | FAAH (0.35) | THRBITGB3ITGA2BHPGDTSHR | |
| SCHEMBL14907487 | 0.83 | THRB (0.45) | THRBITGB3ITGA2BHPGDTSHR | |
| SCHEMBL19789524 | 0.81 | THRB (0.44) | THRBTSHR | |
| SCHEMBL13220826 | 0.80 | ITGB3 (0.49) | THRBITGB3ITGA2BTSHRITGAV | |
| SCHEMBL25500990 | 0.80 | THRB (0.50) | THRBHPGDTSHRS1PR5S1PR4 | |
| SCHEMBL1533011 | 0.79 | CYP2C9 (0.49) | THRBHPGDTSHRS1PR3LMNA | |
| SCHEMBL1533002 | 0.79 | CYP2C9 (0.49) | THRBHPGDTSHRS1PR3LMNA | |
| SCHEMBL1533013 | 0.79 | CYP2C9 (0.49) | THRBHPGDTSHRS1PR3LMNA | |
| SCHEMBL1533004 | 0.79 | CYP2C9 (0.49) | THRBHPGDTSHRS1PR3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2771735-B1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-01-24 | — | — | EP | disclosed |