Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | GUSB | P08236 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15665939 | 0.82 | ALDH1A1 (0.70) | KDM4EALDH1A1LMNANPSR1NPC1 | |
| SCHEMBL9152440 | 0.81 | LTA4H (0.68) | KDM4EALDH1A1TDP1NPC1MAPT | |
| SCHEMBL30167681 | 0.81 | LTA4H (0.68) | KDM4EALDH1A1TDP1NPC1MAPT | |
| SCHEMBL12726668 | 0.81 | LTA4H (0.68) | KDM4EALDH1A1TDP1NPC1MAPT | |
| SCHEMBL12676876 | 0.81 | MEN1 (0.51) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL15056743 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| Ammonia Solution, Strong SCHEMBL7174107 | 0.79 | LTA4H (0.65) | KDM4EALDH1A1TDP1NPC1MAPT | |
| SCHEMBL30063503 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL19229538 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1L3MBTL1LMNATDP1 | |
| SCHEMBL13950894 | 0.79 | KDM4E (0.78) | KDM4EALDH1A1L3MBTL1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393787-B1 | CADHERIN-11 INHIBITORS AND METHODS OF USE THEREOF | UNIV GEORGETOWN (US) | 2018-01-24 | — | — | EP | disclosed |