Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14898392 | 1.00 | CTSS (0.38) | CTSSMMP2MMP3MMP1OPRD1 | |
| SCHEMBL25908942 | 0.93 | TAS1R3 (0.37) | CTSSMMP2MMP3MMP1OPRD1 | |
| SCHEMBL10065865 | 0.84 | CTSS (0.41) | CTSSMMP2MMP3MMP1OPRD1 | |
| SCHEMBL14949074 | 0.81 | CTSS (0.37) | CTSSMMP2MMP3MMP1OPRD1 | |
| SCHEMBL20364905 | 0.75 | HDAC3 (0.38) | — | |
| SCHEMBL19369908 | 0.74 | MAOB (0.39) | — | |
| SCHEMBL22679571 | 0.74 | CTSS (0.33) | CTSSMMP2MMP3MMP1PKM | |
| SCHEMBL14898390 | 0.74 | MAOB (0.39) | — | |
| SCHEMBL18647237 | 0.73 | ALDH1A1 (0.32) | CTSSMMP2MMP3MMP1PKM | |
| SCHEMBL26809260 | 0.73 | ALDH1A1 (0.32) | CTSSMMP2MMP3MMP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937262-B1 | COMPOSITION FOR USE IN TREATING GASTROINTESTINAL DYSMOTILITY | IPSEN PHARMA (FR) | 2019-05-08 | — | — | EP | disclosed |
| EP-2794634-B1 | PROCESS FOR THE SYNTHESIS OF GHRELIN ANALOGUES | IPSEN MFG IRELAND LIMITED (IE) | 2018-01-24 | — | — | EP | disclosed |