Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | ESRRG | P62508 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979028 | 0.82 | KMT2A (0.71) | ALDH1A1HTTAPEX1MAPTTP53 | |
| SCHEMBL12472363 | 0.80 | KMT2A (0.72) | ALDH1A1KDM4EHTTAPEX1MAPT | |
| SCHEMBL21091969 | 0.78 | ALDH1A1 (0.88) | ALDH1A1KDM4EHTTCA2MAPT | |
| SCHEMBL2680413 | 0.77 | LMNA (0.69) | ALDH1A1KDM4EHTTMAPTTP53 | |
| SCHEMBL8404892 | 0.77 | NPC1 (0.62) | APEX1CA1CA9KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL28938255 | 0.76 | ALDH1A1 (0.85) | ALDH1A1KDM4EHTTCA2MAPT | |
| SCHEMBL1917763 | 0.75 | POLA1 (0.72) | ALDH1A1KDM4EHTTCA2MAPT | |
| SCHEMBL15327106 | 0.75 | HCRTR1 (0.49) | ALDH1A1KDM4EHTTCA2MAPT | |
| SCHEMBL10830530 | 0.75 | CYP19A1 (0.69) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL26625346 | 0.74 | KDM4E (0.62) | ALDH1A1KDM4EHTTCA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1372615-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2013-04-24 | — | — | EP | disclosed |
| EP-2308479-A2 | Compounds and compositions for delivering active agents | Emisphere Technologies, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| EP-2308479-A2 | Compounds and compositions for delivering active agents | Emisphere Technologies, Inc. (US) | 2011-04-13 | — | — | EP | disclosed |
| US-7700775-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-04-20 | — | — | US | disclosed |
| US-7700775-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-04-20 | — | — | US | disclosed |
| US-7700775-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-04-20 | — | — | US | disclosed |
| EP-1372615-A4 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2007-09-12 | — | — | EP | disclosed |
| US-20040097500-A1 | Compounds and compositions for delivering active agents | NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) | 2004-05-20 | — | — | US | disclosed |
| CN-1494420-A | Compounds and compositions for the delivery of active ingredients | 埃米斯菲尔技术公司 | 2004-05-05 | — | — | CN | disclosed |
| EP-1372615-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | Emisphere Technologies, Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2002069937-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2002-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097500-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | ALDH1A1 2208/4885KDM4E 4605/4885HTT 547/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.