Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19791937 | 0.86 | HPGD (0.49) | HPGDHDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL12376675 | 0.77 | HDAC2 (0.61) | HPGDHDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL15837149 | 0.77 | MEN1 (0.49) | ALDH1A1CTSBRAB9A | |
| SCHEMBL11904840 | 0.77 | CTSB (0.54) | HPGDHDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL11118046 | 0.73 | HDAC2 (0.56) | HPGDHDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL11904827 | 0.72 | CTSB (0.58) | HPGDHDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL15812190 | 0.71 | ALDH1A1 (0.38) | ALDH1A1KDM4ETDP1RAB9A | |
| SCHEMBL16050236 | 0.71 | HPGD (0.51) | HPGDHDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL15143002 | 0.71 | HDAC2 (0.53) | HPGDHDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL4778260 | 0.71 | HDAC2 (0.61) | HDAC2HDAC8HDAC6HDAC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3272749-A1 | AMINO-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINECARBOXAMIDES AND THEIR USE AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE | Bayer Pharma Aktiengesellschaft (DE) | 2018-01-24 | — | — | EP | disclosed |