Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11904827 | 0.92 | CTSB (0.58) | CTSBHPGDMAPTHTTHDAC3 | |
| SCHEMBL19792104 | 0.77 | HPGD (0.49) | CTSBHPGDMAPTHTTHDAC3 | |
| SCHEMBL16050236 | 0.75 | HPGD (0.51) | CTSBHPGDMAPTHTTHDAC3 | |
| SCHEMBL28356366 | 0.75 | ALDH1A1 (0.51) | GAAALDH1A1KMT2A | |
| SCHEMBL19791937 | 0.74 | HPGD (0.49) | CTSBHPGDMAPTHTTHDAC3 | |
| SCHEMBL3929927 | 0.74 | CTSB (0.52) | CTSBHDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL3929925 | 0.74 | CTSB (0.52) | CTSBHDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL28352595 | 0.74 | RAB9A (0.51) | CTSBMAPTGAAALDH1A1KDM4E | |
| SCHEMBL12376675 | 0.73 | HDAC2 (0.61) | HPGDMAPTHTTHDAC3HDAC2 | |
| SCHEMBL28356497 | 0.71 | RAB9A (0.51) | CTSBMAPTGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486011-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | Bristol-Myers Squibb Company (US) | 2012-08-15 | — | — | EP | disclosed |