Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 7/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30645695 | 1.00 | ACHE (0.44) | ACHEESR1ESR2HSP90AA1SCD5 | |
| SCHEMBL3523748 | 0.84 | ACHE (0.45) | ACHEESR1ESR2HSP90AA1SCD5 | |
| SCHEMBL3524883 | 0.80 | MAPT (0.56) | ACHESCD5LMNAMAPTKDM4E | |
| SCHEMBL32670475 | 0.79 | MAPT (0.43) | ACHEPRNPLMNAMAPTBRD4 | |
| SCHEMBL3526161 | 0.79 | ACHE (0.38) | ACHEESR1ESR2HSP90AA1SCD5 | |
| SCHEMBL13244919 | 0.77 | ESR1 (0.39) | ACHEESR1ESR2HSP90AA1SCD5 | |
| SCHEMBL3522105 | 0.76 | RAB9A (0.44) | ACHELMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL5512412 | 0.76 | ESR1 (0.42) | ACHEESR1ESR2HSP90AA1SCD5 | |
| SCHEMBL3523616 | 0.76 | LMNA (0.47) | ACHEPRNPLMNAMAPTKDM4E | |
| SCHEMBL3523047 | 0.74 | ACHE (0.59) | ACHESCD5MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110506038-B | Pesticidal compounds | 巴斯夫欧洲公司 | 2023-11-24 | — | — | CN | disclosed |
| EP-3601231-B1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2023-05-10 | — | — | EP | disclosed |
| US-11160280-B2 | Pesticial compounds | BASF SE (DE) | 2021-11-02 | — | — | US | disclosed |
| EP-3601231-A1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2020-02-05 | — | — | EP | disclosed |
| US-20200029566-A1 | Pesticial Compounds | BASF SE (DE) | 2020-01-30 | — | — | US | disclosed |
| WO-2018177781-A1 | PESTICIDAL COMPOUNDS | BASF SE (DE) | 2018-10-04 | — | — | WO | disclosed |
| US-9980945-B2 | Benzoisoxazole-substituted compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction | VANDERBILT UNIVERSITY (US) | 2018-05-29 | — | — | US | disclosed |
| US-9980945-B2 | Benzoisoxazole-substituted compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction | VANDERBILT UNIVERSITY (US) | 2018-05-29 | — | — | US | disclosed |
| US-20180021312-A1 | BENZOISOXAZOLE-SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | VANDERBILT UNIVERSITY | 2018-01-25 | — | — | US | disclosed |
| US-20180021312-A1 | BENZOISOXAZOLE-SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | VANDERBILT UNIVERSITY | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180021312-A1 | BENZOISOXAZOLE-SUBSTITUTED COMPOUNDS AS MGLUR4 ALLOSTERIC POTENTIATORS, COMPOSITIONS, AND METHODS OF TREATING NEUROLOGICAL DYSFUNCTION | GRIK4, GRM4, GRM1 | ACHE 664/4885ESR1 987/4885ESR2 901/4885 |
| US-11160280-B2 | Pesticial compounds | PNMT, DDT, NIT2 | ACHE 10/4885ESR1 4814/4885ESR2 4310/4885 |
| US-20200029566-A1 | Pesticial Compounds | PNMT, DDT, NIT2 | ACHE 10/4885ESR1 4814/4885ESR2 4310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.