Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | CCR8 | P51685 | 1/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18015360 | 0.97 | HPGDS (0.49) | HPGDSCYP2A6LMNAKDM4EP4HTM | |
| SCHEMBL21125929 | 0.95 | CHEK2 (0.49) | HPGDSCYP2A6LMNAP4HTMKDR | |
| SCHEMBL20068613 | 0.95 | CHEK2 (0.48) | HPGDSCYP2A6LMNAKDM4EP4HTM | |
| SCHEMBL21125828 | 0.93 | CHEK2 (0.49) | HPGDSCYP2A6LMNAKDM4EP4HTM | |
| SCHEMBL12925598 | 0.93 | KDM4E (0.52) | HPGDSCYP2A6LMNAKDM4EP4HTM | |
| SCHEMBL21397867 | 0.93 | HPGDS (0.47) | HPGDSCYP2A6LMNAKDM4EP4HTM | |
| SCHEMBL21125087 | 0.92 | HSD17B1 (0.49) | HPGDSCYP2A6LMNAKDM4EP4HTM | |
| SCHEMBL21721920 | 0.92 | LDHA (0.50) | HPGDSLDHADHODHHSD17B1HSD17B2 | |
| SCHEMBL28785613 | 0.90 | HPGDS (0.58) | HPGDSCYP2A6LMNAKDM4EP4HTM | |
| SCHEMBL18015574 | 0.90 | LDHA (0.52) | HPGDSLDHAHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | HPGDS 4832/4885CYP2A6 3821/4885LMNA 4536/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | HPGDS 4844/4885CYP2A6 4002/4885LMNA 4570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.