Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.59 |
| ▸ | LPL | P06858 | 8/20 | 0.59 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.57 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19106594 | 1.00 | LIPG (0.59) | LIPGLPLDGAT1P4HBMEN1 | |
| SCHEMBL18015395 | 0.94 | LIPG (0.56) | LIPGLPLDGAT1P4HBMEN1 | |
| SCHEMBL19794486 | 0.94 | LIPG (0.57) | LIPGLPLDGAT1P4HBMEN1 | |
| SCHEMBL18015318 | 0.93 | LIPG (0.57) | LIPGLPLDGAT1P4HBMEN1 | |
| SCHEMBL18015319 | 0.92 | LIPG (0.56) | LIPGLPLDGAT1P4HBMEN1 | |
| SCHEMBL19106625 | 0.91 | LIPG (0.58) | LIPGLPLDGAT1P4HBMEN1 | |
| SCHEMBL18015399 | 0.90 | DGAT1 (0.56) | LIPGLPLDGAT1P4HBHPGDS | |
| SCHEMBL18015711 | 0.90 | DGAT1 (0.49) | LIPGLPLDGAT1ALDH1A1MAPT | |
| SCHEMBL29293266 | 0.89 | LIPG (0.71) | LIPGLPLDGAT1P4HBPDGFRB | |
| SCHEMBL18015320 | 0.88 | LIPG (0.64) | LIPGLPLDGAT1P4HBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601257-B1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-10-27 | — | — | EP | disclosed |
| US-11145828-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-10-12 | — | — | US | disclosed |
| US-11024815-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2021-06-01 | — | — | US | disclosed |
| EP-3526226-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |
| CN-107207550-B | Metal complexes | 默克专利有限公司 | 2020-06-05 | — | — | CN | disclosed |
| US-20200039903-A1 | AROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |
| US-20190252628-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-08-15 | — | — | US | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| EP-3254317-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
| US-20180026209-A1 | Metal Complexes | MERCK PATENT GMBH (DE) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039903-A1 | AROMATIC COMPOUNDS | PAH, ALG3, DDC | LIPG 4416/4885LPL 4826/4885DGAT1 2100/4885 |
| US-11145828-B2 | Metal complexes | AP1M1, AP2M1, AP3M1 | LIPG 3552/4885LPL 3726/4885DGAT1 2072/4885 |
| US-20190252628-A1 | METAL COMPLEXES | AP1M1, AP2M1, AP3M1 | LIPG 3552/4885LPL 3726/4885DGAT1 2072/4885 |
| US-11024815-B2 | Metal complexes | EXOC4, EXOC3, TIMCC | LIPG 4459/4885LPL 4682/4885DGAT1 1835/4885 |
| US-20180026209-A1 | Metal Complexes | AP3M1, AP2M1, SOD1 | LIPG 3693/4885LPL 3416/4885DGAT1 1328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.