Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411191 | 0.87 | KMO (0.32) | ALDH1A1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL17979411 | 0.87 | KMO (0.32) | ALDH1A1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL20424806 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL30836764 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL10041749 | 0.76 | EPAS1 (0.36) | — | |
| SCHEMBL9939364 | 0.74 | GAA (0.38) | ALDH1A1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL12689080 | 0.73 | ALDH1A1 (0.38) | ALDH1A1KDM4ETSHRTDP1MEN1 | |
| SCHEMBL19795354 | 0.72 | NPC1 (0.33) | MAPT | |
| SCHEMBL16558767 | 0.71 | ERN1 (0.36) | TDP1KMT2AERN1 | |
| SCHEMBL15231440 | 0.69 | ALDH1A1 (0.53) | ALDH1A1KDM4ETSHRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018015410-A1 | BICYCLIC PROLINE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2018-01-25 | — | — | WO | disclosed |