Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18361185 | 0.93 | PGR (0.40) | PGRCASP3PDK2GABRA1GABRG2 | |
| SCHEMBL18361105 | 0.92 | GABRA1 (0.42) | PGRCASP3PDK2GABRA1GABRG2 | |
| SCHEMBL20061231 | 0.89 | PGR (0.42) | PGRCASP3PDK2GABRA1GABRG2 | |
| SCHEMBL18361137 | 0.89 | PDK2 (0.40) | PGRCASP3PDK2CYP3A4CYP2C9 | |
| SCHEMBL19755481 | 0.89 | PGR (0.37) | PGRCASP3PDK2GABRA1GABRG2 | |
| SCHEMBL21397002 | 0.89 | CYP11B2 (0.38) | PGRCASP3PDK2GABRA1GABRG2 | |
| SCHEMBL21397202 | 0.87 | PGR (0.38) | PGRCASP3PDK2GABRA1GABRG2 | |
| SCHEMBL19345045 | 0.87 | PGR (0.43) | PGRCASP3PDK2KMT2AMEN1 | |
| SCHEMBL18361130 | 0.87 | PGR (0.40) | PGRCASP3PDK2KMT2AMEN1 | |
| SCHEMBL24923993 | 0.85 | GABRA1 (0.40) | PGRGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10263196-B2 | Organic molecules for use in optoelectronic devices | CYNORA GMBH (DE) | 2019-04-16 | — | — | US | disclosed |
| EP-3138137-B1 | ORGANIC MOLECULES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2018-06-20 | — | — | EP | disclosed |
| US-20180026202-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-01-25 | — | — | US | disclosed |
| US-20180026202-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10263196-B2 | Organic molecules for use in optoelectronic devices | OR10J3, ORC3, OXER1 | PGR 882/4885CASP3 2370/4885PDK2 4386/4885 |
| US-20180026202-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES | ORC3, OR10J3, C1R | PGR 800/4885CASP3 2385/4885PDK2 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.