SCHEMBL1979606

SCHEMBL1979606

O=C(O)/C=C/C(=O)OC(=O)/C=C\C(=O)OC(=O)/C=C/C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 11/20 0.60
TSHR P16473 4/20 0.60
TP53 P04637 1/20 0.60
EGLN1 Q9GZT9 1/20 0.60
EGLN3 Q9H6Z9 1/20 0.60
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
ATM Q13315 1/20 0.38
ALOX15 P16050 1/20 0.37
RECQL P46063 1/20 0.37
HSD17B10 Q99714 1/20 0.37
GABRR1 P24046 2/20 0.35
GABRR2 P28476 2/20 0.35
BLM P54132 2/20 0.35
GABRR3 A8MPY1 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL27560148 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1238140 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL499484 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL63810 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
Maleic Acid SCHEMBL5822456 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL4949804 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
Maleic Acid SCHEMBL8418674 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL2402992 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
Maleic Acid SCHEMBL20487518 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL27731205 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230011640-A1 METHODS FOR RECOVERING ORGANIC SALTS FROM INDUSTRIAL PROCESS STREAMS CYTEC INDUSTRIES INC. (US) 2023-01-12 US disclosed
EP-4073000-A1 METHODS FOR RECOVERING ORGANIC SALTS FROM INDUSTRIAL PROCESS STREAMS Cytec Industries, Inc. (US) 2022-10-19 EP disclosed
WO-2021118938-A1 METHODS FOR RECOVERING ORGANIC SALTS FROM INDUSTRIAL PROCESS STREAMS CYTEC INDUSTRIES INC. (US) 2021-06-17 WO disclosed
CN-111465394-A Drugs and compositions for ocular delivery 灰色视觉公司 2020-07-28 CN disclosed
US-8435411-B2 Methods and compositions for the removal of impurities from an impurity-loaded organic salt CYTEC TECHNOLOGY CORP. (US) 2013-05-07 US disclosed
EP-2512614-A1 METHODS AND COMPOSITIONS FOR THE REMOVAL OF IMPURITIES FROM AN IMPURITY-LOADED IONIC LIQUID Cytec Technology Corp. (US) 2012-10-24 EP disclosed
WO-2011081764-A1 METHODS AND COMPOSITIONS FOR THE REMOVAL OF IMPURITIES FROM AN IMPURITY-LOADED IONIC LIQUID CYTEC TECHNOLOGY CORP. (US) 2011-07-07 WO disclosed
US-20110140037-A1 METHODS AND COMPOSITIONS FOR THE REMOVAL OF IMPURITIES FROM AN IMPURITY-LOADED ORGANIC SALT CYTEC TECHNOLOGY CORP. (US) 2011-06-16 US disclosed
CN-101534808-A Modified release formulations of bupropion salts BIOVAIL LAB INT SRL (BB) 2009-09-16 CN disclosed
CN-1033026-C Improved temperature control process for the preparation of 2, 2' -oxodisuccinates as laundry detergent builders PROCTER & GAMBLE (US) 1996-10-16 CN disclosed
CN-1117042-A Improved, controlled temperature process for making2,2'-oxodisuccinates useful as laundry detergent builders PROCTER & GAMBLE (US) 1996-02-21 CN disclosed
US-5298634-A Reacting maleate or mixture with 2,2-oxodisuccinate, fumarate and malate, calcium, magnesium divalent cations and rendering reaction mixture alkaline by adding hydroxide THE PROCTER & GAMBLE COMPANY (US) 1994-03-29 US disclosed
US-4910267-A Sulfur vulcanized copolymer of an unsaturated nitrile, conjugated diene and an unsaturated carboxylic group NIPPON ZEON CO., LTD. (JP) 1990-03-20 US disclosed
US-4847262-A CENTRAL NERVOUS SYSTEM SCHERING AKTIENGESELLSCHAFT (DE) 1989-07-11 US disclosed
CN-85104237-A The preparation method of 3-amino-pyrazol base (3,4-d) pyrimidine derivatives 1986-12-03 CN disclosed
US-4379790-A (Erolinyl)-N,N-diethylurea derivatives, and their preparation and use SCHERING AKTIENGESELLSCHAFT (DE) 1983-04-12 US disclosed
US-4318911-A 5,6-Diaryl-1,2,4-triazines as topical antithrombotic agents ELI LILLY AND COMPANY (US) 1982-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110140037-A1 METHODS AND COMPOSITIONS FOR THE REMOVAL OF IMPURITIES FROM AN IMPURITY-LOADED ORGANIC SALT OSTC, SLC10A6, SLC22A8 HCAR2 4581/4885TSHR 4622/4885TP53 1533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.