SCHEMBL499484

SCHEMBL499484

O=C(O)/C=C\C(=O)OC(=O)/C=C\C(=O)OC(=O)/C=C\C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 11/20 0.60
TSHR P16473 4/20 0.60
TP53 P04637 1/20 0.60
EGLN1 Q9GZT9 1/20 0.60
EGLN3 Q9H6Z9 1/20 0.60
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
KDM4E B2RXH2 1/20 0.40
MAPT P10636 1/20 0.40
ATM Q13315 1/20 0.38
ALOX15 P16050 1/20 0.37
RECQL P46063 1/20 0.37
HSD17B10 Q99714 1/20 0.37
GABRR1 P24046 2/20 0.35
GABRR2 P28476 2/20 0.35
BLM P54132 2/20 0.35
GABRR3 A8MPY1 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fumaric Acid SCHEMBL27560148 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1238140 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL63810 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL1979606 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
Maleic Acid SCHEMBL5822456 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL4949804 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
Maleic Acid SCHEMBL8418674 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
SCHEMBL2402992 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
Maleic Acid SCHEMBL20487518 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3
Fumaric Acid SCHEMBL27731205 1.00 HCAR2 (0.60) HCAR2TSHRTP53EGLN1EGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10894443-B2 Expansible barrier film assemblies EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-01-19 US claimed
EP-3233482-B1 EXPANSIBLE BARRIER FILM ASSEMBLIES EXXONMOBIL CHEMICAL PATENTS INC (US) 2020-06-17 EP claimed
CN-105385380-B The textile fabric of binder consolidation, its manufacturing method and application thereof 约翰斯曼维尔欧洲有限公司 2019-07-09 CN claimed
US-10201909-B2 Treated wood material DOW GLOBAL TECHNOLOGIES LLC (US) 2019-02-12 US claimed
US-10119213-B2 Binder-consolidated textile fabric, method for producing it, and use thereof JOHNS MANVILLE (US) 2018-11-06 US claimed
US-20170313132-A1 Expansible Barrier Film Assemblies EXXONMOBIL CHEMICAL PATENTS INC. 2017-11-02 US claimed
EP-3233482-A1 EXPANSIBLE BARRIER FILM ASSEMBLIES ExxonMobil Chemical Patents Inc. (US) 2017-10-25 EP claimed
US-20170129131-A1 TREATED POROUS MATERIAL DOW GLOBAL TECHNOLOGIES LLC 2017-05-11 US claimed
EP-3160698-A1 TREATED POROUS MATERIAL Dow Global Technologies LLC (US) 2017-05-03 EP claimed
US-20160053418-A1 Binder-consolidated textile fabric, method for producing it, and use thereof JOHNS MANVILLE 2016-02-25 US claimed
US-20050187112-A1 Composition and method for a dual-function soil-grouting excavating or boring fluid KB INTERNATIONAL, LLC (US) 2005-08-25 US claimed
US-6794482-B2 Adhesion promoter additive comprising an unsaturated, amorphous polyester DEGUSSA AG (DE) 2004-09-21 US claimed
US-20040054075-A1 Adhesion promoter additive comprising an unsaturated, amorphous polyester DEGUSSA AG (DE) 2004-03-18 US claimed
US-20030077307-A1 Film-forming compositions for protecting skin from body fluids and articles made therefrom THE PROCTER & GAMBLE COMPANY 2003-04-24 US claimed
US-6498272-B1 OXIDIZING ACROLEIN AND/OR PROPENE, QUENCHING TO COOL, DISTILLING, CLEAVING ACRYLIC ACID OLIGOMERS, CONDENSING BASF AKTIENGESELLSCHAFT (DE) 2002-12-24 US claimed
CN-1286139-A Improved catalyst for preparing 1,4-butanediol by hydrogenation of maleic acid MOBIL OIL (US) 2001-03-07 CN claimed
US-5866628-A FORMALDEHYDE OLIGOMER OR A CYCLIC-ALIPHATIC OLIGOMER; FLUORESCENT DYE; AND PHOTOPOLYMERIZABLE VEHICLE. DAY-GLO COLOR CORP. (US) 1999-02-02 US claimed
US-5472684-A Antibacterial mixture of thymol, eugenol, and/or a sesquiterpene alcohol; mouthwashes, dentifrices; synergistic COLGATE PALMOLIVE COMPANY (US) 1995-12-05 US claimed
US-5130470-A Trifluoromethanesulfonic acid as a polymerization catalyst or a fluorinated olefin polymer modified with sulfonate E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-14 US claimed
US-4116903-A Alkyd-supported emulsion interpolymers and methods for preparation P.R.A. LABORATORIES INCORPORATED (US) 1978-09-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030077307-A1 Film-forming compositions for protecting skin from body fluids and articles made therefrom CUTA, NEFM, AQP1 HCAR2 4687/4885TSHR 4758/4885TP53 3944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.